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Penn Discovers New, Rare Mechanism for ALL to Relapse after CAR T Cell Therapy
A single leukemia cell, unknowingly engineered with the leukemia-targeting chimeric antigen receptor (CAR) lentivirus and infused back into a patient, was able to reproduce and cause a deadly...
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Genetic Variants Reveal New Targets for Chronic Kidney Disease Treatment
By investigating how genetic variations drive the expression of genes within the filtering cells of the kidney, researchers have found new pathways to explain CKD development and could inform its...
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The Next Frontier of Precision Medicine: Parkinson’s Disease
The MIND Initiative, led by Alice Chen-Plotkin, MD, the Parker Family Associate Professor of Neurology, will collect medical information such as family history and personal symptoms of Parkinson’s as...
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Seven Penn Researchers Receive NIH Director’s Awards
Seven University of Pennsylvania researchers, including five from the Perelman School of Medicine at the University of Pennsylvania, have been selected to receive highly competitive National Institutes...
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Kidney Care Conflicts of Interest: Penn Medicine Experts Call for...
Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on...
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Analysis Reveals Genomic Effects of a New Cancer Treatment Now in Clinical...
A twist on the molecular mechanism of how a new cancer drug works could aid in better identifying the best treatments for patients for an array of cancers.
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Penn Medicine’s Orphan Disease Center Announces Three New Programs of...
The Orphan Disease Center in the Perelman School of Medicine at the University of Pennsylvania has established three new Programs of Excellence that will focus on innovative gene therapies to treat...
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Guided by CRISPR, Prenatal Gene Editing Shows Proof-of-Concept in Treating...
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
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There’s a Better Way to Decipher DNA’s Epigenetic Code to Identify Disease
A new method for sequencing the chemical groups attached to the surface of DNA is paving the way for better detection of cancer and other diseases, according to research from the Perelman School of...
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Penn Medicine Welcomes Inaugural Chief Research Information Officer
Danielle Mowery, PhD, has joined Penn Medicine as its inaugural chief research information officer (CRIO) and leader of the Clinical Research Informatics Core (CIC) in the Institute for Biomedical...
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Penn Medicine’s OncoLink Receives 2018 CPEN Excellence in Patient Education...
The Cancer Patient Education Network (CPEN) honored the Patient Education Team from Penn Medicine’s OncoLink with the 2018 Excellence in Patient Education Award. The award recognizes individuals or...
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Molecular Details of Protein Reveal Glimpse into How Kidney Stones Form
Kidney stones—solid, pebble-like grit that forms when too much of certain minerals like calcium are in the urine—can strike men, women, and increasingly, children, and the presence and pain of stones...
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Penn Medicine Launches Initiative to Transform Electronic Health Record Systems
Each year, advances make medical devices safer and propel the development of ever-more targeted drugs and precise surgeries. Digital health technology is also emerging as a force to revolutionize...
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Invitation to Cover: Health Care Makerthon at Penn
A two-day, marathon competition to win $10,000 hosted by Penn Health-Tech, a partnership of Penn Medicine and Penn Engineering, will feature 22 teams of Penn students creating devices with the...
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Blood Test Identifies More Treatable Cancer Mutations Than Tissue Biopsy Alone
In one of the largest clinical studies to ever examine the impact of using a blood test to detect treatable mutations in non-small cell lung cancer (NSCLC), researchers from the Abramson Cancer Center...
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Four Penn Faculty Members Elected to National Academy of Medicine
Four faculty members from the Perelman School of Medicine at the University of Pennsylvania have been elected to the National Academy of Medicine (NAM), one of the nation's highest honors in biomedicine.
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Penn Medicine’s Community Health Worker Model Recognized by the U.S....
A team from Penn Medicine that runs a program to improve health outcomes for veterans received a “Gold Status” Diffusion of Excellence award from the Veterans Health Administration (VHA), the health...
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Making Gene Therapy Delivery Safer and More Efficient
Viral vectors used to deliver gene therapies undergo spontaneous changes during manufacturing which affects their structure and function, found researchers from the Perelman School of Medicine at the...
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Cancer Patients Can Now Use Skin Creams During Radiation Therapy
Contrary to the advice most cancer patients receive when they go through radiation treatment, topical skin treatments, unless applied very heavily, do not increase the radiation dose to the skin and...
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Future Fertility: Giving Hope to Men Who Received Childhood Cancer Treatment
Researchers have discovered a way to grow human stem cells destined to become mature sperm in an effort to provide fertility options later in life to males who are diagnosed with cancer and undergo...
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