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Semaglutide and mental health

Taking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders, according...

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100x Improvement in Sight Seen After Gene Therapy Trial

Patients with a rare inherited disease affecting their sight experienced quick vision improvements that sustained for the full year-long study.

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Julia Borrelli to chair ACC Director's Leadership Council

Julia “Julie” Borrelli has been appointed chair of the Abramson Cancer Center Director's Leadership Council, succeeding Richard S. Schiffrin, Esq, who served as chair for five years. Borelli’s...

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Gene Therapy is Potentially Life-Changing for Hemophilia B

Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to newly published clinical trial results that formed...

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Katalin Karikó Named to Distinguished Daughters of Pennsylvania

Co-Nobel Prize winner and mRNA vaccine pioneer Katalin Karikó, PhD, was inducted to the Distinguished Daughters of Pennsylvania Class of 2024 by Governor Josh Shapiro at a formal ceremony at the...

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Penn Medicine at the 2024 ASTRO Annual Meeting

Penn researchers will present clinical trial results, new data on FLASH radiation therapy, updates on expanding global access to radiation therapy, and more at the 2024 American Society for Radiation...

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$18M grant investigates Cognitive decline in Lewy body diseases

Penn researchers to investigate causes of cognitive decline in Lewy body diseases with $18M grant

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Access to geriatric care in eastern PA with $5M grant

Access to geriatric care expanded in eastern PA with $5M grant

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$14M grant funds rare metabolic disease gene-editing research

A $14M grant will fund research on gene-editing therapies for rare metabolic diseases at the Perelman School of Medicine and Children’s Hospital of Philadelphia. The research will focus specifically on...

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Prevention Research Center awarded $6.5 million CDC grant

The University of Pennsylvania Prevention Research Center has been awarded a grant totaling $6.5 million over five years from the CDC for community-based prevention and public health research, with a...

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Penn Medicine and CHOP Create Vaccine to Prevent and Treat C.diff

The vaccine is the first mRNA vaccine against C. difficile and would be the first vaccine in general to successfully ward off the bacterial infection.

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Long Term Antiviral Use is Key to Ocular Shingles Treatment

Shingles affects eyes of 100,000 people each year in the US, but there has been no long-term treatment for it. Now, researchers have shown that extended use of an existing treatment reduces the chance...

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2024 Basser Global Prize Awarded to UT Health’s Patrick Sung

The Basser Center for BRCA has announced Patrick Sung, DPhil, of The University of Texas Health Science Center at San Antonio, as the recipient of the 2024 Basser Global Prize for his cutting-edge work...

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Six Penn experts elected to National Academy of Medicine

The honor recognizes individuals who have demonstrated outstanding professional achievement and commitment to service.

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Garret A FitzGerald MD receives Award for Distinguished Research

Garret FitzGerald, MD, FRS, is the fifth Penn Medicine researcher in ten years to be honored with this award. His work focuses on the study of cardiovascular health with a focus on pain medicines.

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In-game assists turn to violence prevention dollars

For every assist this season, Penn Medicine and the 76ers will put $76 toward six grassroots violence prevention programs.

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Psoriasis Patients Likely to Use Light Therapy Treatment at Home

Penn Medicine study suggests that patients with plaque or guttate psoriasis can get clearer skin with at-home treatment instead of at doctors’ offices

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90 percent of peptides discovered had antimicrobial properties

Newly-discovered peptides disrupt the protective membranes surrounding bacterial cells.

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For 20th Time, Penn Medicine Named to ‘Most Wired’

Penn Medicine’s efforts to integrate and implement information technology landed it on prestigious tech list for the 20th time.

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White House Names ACC Neuro-Oncologist a Cancer Moonshot Scholar

The Biden Cancer Moonshot Program named Penn Medicine’s Richard E. Phillips, MD, PhD, Chief of the Division of Neuro-Oncology and an assistant professor of Neurology, a Cancer Moonshot Scholar.

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Study of chemical exposure, dementia risk funded by $11M grant

To better understand how day-to-day exposures to chemicals earlier in life can contribute to conditions like Alzheimer’s disease later on, researchers received an $11 million National Institutes of...

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Study links liver-brain communication to daily eating patterns

A Penn study showed disconnecting nerve connection corrects overeating and weight gain caused by a defective “liver clock".

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Penn Medicine, AHA Team Up to Take Down High Blood Pressure

Penn Medicine, the American Heart Association, and community organizations team up to take down high blood pressure in West and Southwest Philadelphia.

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Report comes as Washington considers ending the use of 14C jobs

Findings include policy considerations for lawmakers to consider as a new Congress takes shape.

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Inconsistencies of Genetic Markers for Predicting Heart Disease

Penn study suggests polygenic risk scores may provide conflicting results for detecting heart disease risk.

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UPHS releases sweeping Climate and Sustainability Action Plan

The plan outlines an ambitious roadmap to become the nation’s most eco-friendly health care organization.

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Health Care Reviews Tank Following COVID Pandemic

After the COVID-19 pandemic struck, online reviews of health care facilities dropped significantly, and they have not yet fully recovered, according to a new analysis led by researchers at the Perelman...

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Penn Medicine at the 2024 ASH Annual Meeting

Researchers from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in blood cancer and benign hematology research at...

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Penn Medicine and IBX Announce New Long-Term Agreement

The University of Pennsylvania Health System and Independence Blue Cross have reached a long-term agreement on reimbursement rates for a new contract renewal, which would take effect on July 1, 2025.

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Penn Medicine partners with Mark Cuban’s Cost Plus Drugs

Penn Medicine has partnered with Mark Cuban's Cost Plus Drug Company through its innovative Cost Plus Marketplace in a strategic alliance that will allow Penn Medicine to secure the top 100 most...

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Keto diet metabolite may power up CAR T cells to kill cancer

A simple dietary supplement may provide a new, cost-effective approach to boost CAR T cell function, according to early findings shared at the ASH Annual Meeting.

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GBM organoids model patient response to CAR T cell therapy

For the first time, Penn Medicine researchers used lab-grown organoids created from tumors of individuals with glioblastoma to accurately model a patient’s response to CAR T cell therapy in real time.

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Researchers to advance imaging of Parkinson’s diseases

A Penn-led collaboration of radiology, computational chemistry, and neurology experts will identify and test new tracers for PET scans to help diagnose and monitor disease.

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Generic platinum chemo shortages did not increase deaths

An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin...

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Driving down postpartum high blood pressure

Perelman School of Medicine researchers are launching a $12.5 million study to improve postpartum blood pressure management and long-term cardiovascular health for patients with hypertensive disorders...

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Two health startups receive Penn Medicine-Wharton funds

The startups seek to address workplace burnout and racial inequity in maternal care.

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Cellular structures link to kidney cancer treatment outcomes

New research from the Berger Lab reveals that nuclear speckle patterns in kidney tumors may influence treatment outcomes for clear cell renal cell carcinoma, offering a path toward more personalized...

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New CAREs grants behind Penn Medicine volunteer projects

37 projects were awarded funds to support health system and medical school volunteer work.

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Genetic testing for risk of opioid misuse remains unproven

New research questions the usefulness of 15 genetic variants from an algorithm meant to predict opioid use disorder risk that was recently granted pre-marketing approval by the Food and Drug...

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Using AI to uncover hospital patients’ long COVID care needs

A new machine learning technique could help inform clinical decision- making across hospital systems to address the challenges of long COVID-19 care.

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Racism linked to higher postpartum blood pressure

Mothers of color who faced racism or microaggressions during obstetric care had higher blood pressure after delivering their babies compared to people of color who did not report racism during their care.

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AI analyzes 30k data points per pixel in cancer search

A new AI tool can search through data and images for much more precise information on cancer treatment effectiveness than what can be seen in CT or MRI scans.

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Penn Medicine scientists develop tiny anticancer weapon

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of...

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Researchers develop guidelines to diagnose common memory disorder

Limbic-predominant age-related TDP-43 encephalopathy can progress slower and cause less impairment of cognitive functions than other types of dementia.

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Penn Medicine names Pari V. Pandharipande Chair of Radiology

Pari V. Pandharipande, MD, MPH, FACR, a nationally renowned physician-scientist at The Ohio State University (OSU) College of Medicine and Wexner Medical Center, has been named Penn Medicine Chair of...

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Research sheds light on risks related to firearms and opioids

Research could shed more light on the risks related to firearms and opioids.

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Susan Domchek honored by ASCO for cancer prevention work

Susan M. Domchek, MD, FASCO, has been recognized by the American Society of Clinical Oncology with one of the society’s highest honors, as the 2025 recipient of the ASCO-American Cancer Society Cancer...

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No evidence that CAR T cell therapy causes secondary cancers

Researchers found no evidence that CAR T cell therapy caused any type of secondary cancer in the modified T cells, according to new analysis from the Perelman School of Medicine and the Abramson Cancer...

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7 Penn, CHOP faculty elected to ASCI

The members are among 99 physician-scientists from 46 institutions recognized for excellence across academic medicine.

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AI tool helps find life-saving medicine for rare disease

Set to enter hospice care, a patient with idiopathic multicentric Castleman’s disease is now in remission after treatment with a medication predicated as the top treatment by an AI-guided analysis.

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