ASCO: New ‘Armored’ CAR produces significant responses
A new “armored” form of CAR T cell therapy may be able to help patients with non-Hodgkin lymphoma whose cancers do not respond to currently available CAR T cell therapies. The Phase I clinical trial...
View ArticleRare Disease's Mutation Could Explain More Common Conditions
New research shows that when people are born with mutated TREX1, it causes catastrophic damage to the DNA over time, resulting in a deadly rare disease called retinal vasculopathy with cerebral...
View ArticleStroke risk increases in individuals with multiple head injuries
The rate of stroke, in individuals with no history of prior stroke, was 34 percent higher in individuals who experienced at least one head injury than in their peers with no head injury.
View ArticlePenn uses AI to uncover antibiotics in microbial dark matter
The unprecedented effort yielded nearly one million potential antibiotic compounds, with dozens showing promising activity in initial tests against disease-causing bacteria.
View ArticleFirst study of civilian space crew charts course for research
Penn Medicine experts investigated physiological and mental changes in the Inspiration4 crew, the first all-civilian space mission.
View ArticleRare Bone Marrow Cells Revealed in New, Comprehensive ‘Atlas’
A Penn Medicine and Children’s Hospital of Philadelphia team detailed little-understood cells within bone marrow that contribute to the fight against leukemia and other conditions.
View ArticlePotential new strategy for advanced lung cancer
High response rates for patients with stage 4 lung cancer after anti-inflammatory drug added temporarily to immune checkpoint inhibitor therapy
View ArticleLung transplant outcomes from organ donor care facilities
A new study by Penn researchers examined, for the first time, the differences in lung transplant graft outcomes from organs recovered from the two types of deceased organ donor care facilities...
View ArticleNew Approach Accurately Identifies Medications Toxic to the Liver
A Penn Medicine-led study developed a novel approach to using health care data to measure rates of liver injury since the current method of counting cases is not providing an accurate picture.
View Article$10M NIH grant investigates link between TBI and dementia
A team of researchers led by Penn Medicine will investigate the link between traumatic brain injuries and Alzheimer’s disease and related dementias with a $10 million grant from the National Institute...
View ArticleWhen there’s money to lose, phone usage while driving drops
Penn Medicine researchers discovered that feedback plus cash incentives designed with insights from behavioral science reduces phone use while driving.
View ArticleNew therapy reduces treatment time for bipolar disorder
Potential therapy can be completed in five days of treatment, compared to 4-6 weeks for standard Transcranial Magnetic Simulation treatments.
View ArticleDouglas B. Cines Honored for Contributions to Hematology
Douglas B. Cines, MD, has been named the 2024 recipient of the Henry M. Stratton Medal for basic science from the American Society of Hematology (ASH).
View ArticleThe Importance of Diversity in Understanding Health Disparities
Partnership with the Million Veteran Program finds that genetic data in non-European population aligns with reporting from underrepresented groups.
View ArticleNeha Vapiwala, MD, named president-elect of ASTRO
Neha Vapiwala, MD, has been named president-elect of American Society for Radiation Oncology (ASTRO).
View ArticleKnockout of CD5 on CAR T Cells Boosts Anti-Tumor Efficacy
In a study published today in Science Immunology, Penn Medicine researchers identify CD5 as an immune checkpoint protein and a potential target of future cancer therapies.
View ArticleHow a Bacterium Supports Healing of Chronic Diabetic Wounds
The findings could be used to develop topical or bacterial-based treatments for patients with wounds that do not heal well on their own.
View ArticleTo Get Drivers to Put Down Their Phones, Make it a Game
A large trial of strategies to reduce distracted driving showed that those that were “gamified” yielded a lasting reduction in handheld phone usage while driving.
View ArticleBlack Americans injured by firearms 10 times more than whites
Black Americans experienced nonfatal firearm injuries 10 times more than White Americans in 2019 and 2020, and Black boys and men experienced the highest rate of firearm injuries caused by assault and...
View ArticleUPHS and Doylestown Health Sign Definitive Agreement
Bucks County system’s integration into UPHS will expand access to advanced healthcare for patients and families in the suburbs of Philadelphia.
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