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Tip of the Iceberg: Genetic Screening in Yeast Reveals New Candidate Gene for Lou Gehrig''s Disease, Penn Study Finds

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Amyotrophic lateral sclerosis (ALS), or Lou Gehrig''s disease, is a universally fatal neurodegenerative disease. Mutations in two related proteins, TDP-43 and FUS, cause some forms of ALS. Specifically, these two proteins are RNA-binding proteins that connect to RNA to regulate the translation of proteins and other cellular functions such as RNA splicing and editing. In a new study, researchers...

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