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Penn Researchers Explain How Ends of Chromosomes are Maintained for Cancer Cell Immortality

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Maintaining the ends of chromosomes, called telomeres, is a requisite feature of cells that are able to continuously divide and also a hallmark of human cancer. "Telomeres are much like the plastic cap on the ends of shoelaces -- they keep the ends of DNA from fraying," says Roger Greenberg, MD, PhD. In a new study published this week in Cell, he and his colleagues describe a mechanism for how...

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