Study links liver-brain communication to daily eating patterns
A Penn study showed disconnecting nerve connection corrects overeating and weight gain caused by a defective “liver clock".
View ArticlePenn Medicine, AHA Team Up to Take Down High Blood Pressure
Penn Medicine, the American Heart Association, and community organizations team up to take down high blood pressure in West and Southwest Philadelphia.
View ArticleReport comes as Washington considers ending the use of 14C jobs
Findings include policy considerations for lawmakers to consider as a new Congress takes shape.
View ArticleInconsistencies of Genetic Markers for Predicting Heart Disease
Penn study suggests polygenic risk scores may provide conflicting results for detecting heart disease risk.
View ArticleUPHS releases sweeping Climate and Sustainability Action Plan
The plan outlines an ambitious roadmap to become the nation’s most eco-friendly health care organization.
View ArticleHealth Care Reviews Tank Following COVID Pandemic
After the COVID-19 pandemic struck, online reviews of health care facilities dropped significantly, and they have not yet fully recovered, according to a new analysis led by researchers at the Perelman...
View ArticlePenn Medicine at the 2024 ASH Annual Meeting
Researchers from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in blood cancer and benign hematology research at...
View ArticlePenn Medicine and IBX Announce New Long-Term Agreement
The University of Pennsylvania Health System and Independence Blue Cross have reached a long-term agreement on reimbursement rates for a new contract renewal, which would take effect on July 1, 2025.
View ArticlePenn Medicine partners with Mark Cuban’s Cost Plus Drugs
Penn Medicine has partnered with Mark Cuban's Cost Plus Drug Company through its innovative Cost Plus Marketplace in a strategic alliance that will allow Penn Medicine to secure the top 100 most...
View ArticleKeto diet metabolite may power up CAR T cells to kill cancer
A simple dietary supplement may provide a new, cost-effective approach to boost CAR T cell function, according to early findings shared at the ASH Annual Meeting.
View ArticleGBM organoids model patient response to CAR T cell therapy
For the first time, Penn Medicine researchers used lab-grown organoids created from tumors of individuals with glioblastoma to accurately model a patient’s response to CAR T cell therapy in real time.
View ArticleResearchers to advance imaging of Parkinson’s diseases
A Penn-led collaboration of radiology, computational chemistry, and neurology experts will identify and test new tracers for PET scans to help diagnose and monitor disease.
View ArticleGeneric platinum chemo shortages did not increase deaths
An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin...
View ArticleDriving down postpartum high blood pressure
Perelman School of Medicine researchers are launching a $12.5 million study to improve postpartum blood pressure management and long-term cardiovascular health for patients with hypertensive disorders...
View ArticleTwo health startups receive Penn Medicine-Wharton funds
The startups seek to address workplace burnout and racial inequity in maternal care.
View ArticleCellular structures link to kidney cancer treatment outcomes
New research from the Berger Lab reveals that nuclear speckle patterns in kidney tumors may influence treatment outcomes for clear cell renal cell carcinoma, offering a path toward more personalized...
View ArticleNew CAREs grants behind Penn Medicine volunteer projects
37 projects were awarded funds to support health system and medical school volunteer work.
View ArticleGenetic testing for risk of opioid misuse remains unproven
New research questions the usefulness of 15 genetic variants from an algorithm meant to predict opioid use disorder risk that was recently granted pre-marketing approval by the Food and Drug...
View ArticleUsing AI to uncover hospital patients’ long COVID care needs
A new machine learning technique could help inform clinical decision- making across hospital systems to address the challenges of long COVID-19 care.
View ArticleRacism linked to higher postpartum blood pressure
Mothers of color who faced racism or microaggressions during obstetric care had higher blood pressure after delivering their babies compared to people of color who did not report racism during their care.
View ArticleAI analyzes 30k data points per pixel in cancer search
A new AI tool can search through data and images for much more precise information on cancer treatment effectiveness than what can be seen in CT or MRI scans.
View ArticlePenn Medicine scientists develop tiny anticancer weapon
A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of...
View ArticleResearchers develop guidelines to diagnose common memory disorder
Limbic-predominant age-related TDP-43 encephalopathy can progress slower and cause less impairment of cognitive functions than other types of dementia.
View ArticlePenn Medicine names Pari V. Pandharipande Chair of Radiology
Pari V. Pandharipande, MD, MPH, FACR, a nationally renowned physician-scientist at The Ohio State University (OSU) College of Medicine and Wexner Medical Center, has been named Penn Medicine Chair of...
View ArticleResearch sheds light on risks related to firearms and opioids
Research could shed more light on the risks related to firearms and opioids.
View ArticleSusan Domchek honored by ASCO for cancer prevention work
Susan M. Domchek, MD, FASCO, has been recognized by the American Society of Clinical Oncology with one of the society’s highest honors, as the 2025 recipient of the ASCO-American Cancer Society Cancer...
View ArticleNo evidence that CAR T cell therapy causes secondary cancers
Researchers found no evidence that CAR T cell therapy caused any type of secondary cancer in the modified T cells, according to new analysis from the Perelman School of Medicine and the Abramson Cancer...
View Article7 Penn, CHOP faculty elected to ASCI
The members are among 99 physician-scientists from 46 institutions recognized for excellence across academic medicine.
View ArticleAI tool helps find life-saving medicine for rare disease
Set to enter hospice care, a patient with idiopathic multicentric Castleman’s disease is now in remission after treatment with a medication predicated as the top treatment by an AI-guided analysis.
View ArticleHigher cancer risk for kidney transplant recipients linked to EBV
Over 90% of U.S. adults have had Epstein-Barr virus (EBV), but EBV-negative kidney transplant patients face a serious risk. A Penn study finds they may develop PTLD, a life-threatening immune disorder,...
View ArticleResearchers create genetic map tied to kidney disease
Creation of the most complete map of more than 1000 genes that influence kidney function could help experts diagnose and design targeted treatments for kidney disease.
View ArticleRate of suicide higher in individuals with headaches
Suicide attempt and completion was highest among individuals with headaches from head injuries, but also elevated in individuals with mild headaches, Penn research finds.
View ArticleTransformational gift to accelerate Penn Medicine care
The Pavilion will be renamed to recognize Catherine and Anthony Clifton’s historic philanthropic commitment that will usher in a new era of innovation.
View ArticleText message tool addresses "time toxicity" for cancer patients
A pilot study shows it’s possible to use digital technology to safely reduce the amount of time some patients with cancer spend receiving care.
View ArticleAI ‘scribe’ increases face-to-face time with patients
Using an artificial intelligence-powered system to “listen” to patient visits and take notes increased clinician face time with patients and reduced after-hours work.
View ArticleNew mRNA therapy could repair damaged lungs
Penn researchers designed an organ-specific mRNA and lipid nanoparticle therapy which could lead to new targeted treatments for damaged organs.
View Article3 Penn papers in Clinical Research Forum Top 10
Three studies led by Perelman School of Medicine faculty were chosen among the nation’s most impactful clinical research publications.
View ArticleDiabetic eye disease up, but most severe forms down
Data showed that while diabetes-related eye diseases doubled since 2014, the most severe forms of the disease have decreased.
View ArticlePatients with disabilities less likely to feel respect from docs
Analysis shows that patients with disabilities were both less likely to feel respect from their doctors and less likely to feel their doctors explained things well.
View ArticleFour Penn cancer researchers elected to the AACR Academy
Garrett M. Brodeur, MD, Susan Domchek, MD, Stephan Grupp, MD, PhD, and Robert Vonderheide, MD, DPhil, have been elected to the AACR Academy.
View ArticleControlling cell acidity could be key to autoimmune disease
Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one protein’s role in helping another protein control cell acidity.
View ArticleOlder adults may be more resistant to bird flu
Older adults who were exposed to seasonal flu viruses that circulated prior to 1968 are more likely to have some protection against H5N1, and that children would benefit more from H5N1 vaccines.
View ArticleImmunotherapy boosts KRAS-targeted therapy in pancreatic cancer
Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.
View ArticleSmall incentives drive lasting seatbelt habits
When drivers of connected cars were promised a share of reward money for weekly streaks of always wearing their seatbelts, they buckled up more, even after the program ended.
View ArticleEarly anti-obesity medications boost weight loss
Struggling to lose weight with diet & exercise? New research shows adding anti-obesity meds after just 1 month of therapy doubles weight loss, offering hope for those who falter with lifestyle...
View ArticleDNA-LNPs: A Safer, Longer-Lasting Gene Therapy Breakthrough
The first safe & effective DNA-loaded lipid nanoparticles (DNA-LNPs) picks up where mRNA left off.
View ArticleMeniscus injuries may soon be treated by customizable hydrogel
A new 3D-printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears.
View ArticleDoylestown Health joins University of Pennsylvania Health System
The Bucks County system’s integration into UPHS will expand access to advanced health care for patients and families in the suburbs of Philadelphia.
View ArticleCAREs grant helps patients share their own health care story
24 grants help to power community service projects led by faculty, staff and students.
View ArticleCould laughing gas be used for depression treatment?
A Penn study reveals laughing gas targets brain cells to lift mood fast in mice, offering hope for treatment-resistant cases.
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