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For 20th Time, Penn Medicine Named to ‘Most Wired’

Penn Medicine’s efforts to integrate and implement information technology landed it on prestigious tech list for the 20th time.

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White House Names ACC Neuro-Oncologist a Cancer Moonshot Scholar

The Biden Cancer Moonshot Program named Penn Medicine’s Richard E. Phillips, MD, PhD, Chief of the Division of Neuro-Oncology and an assistant professor of Neurology, a Cancer Moonshot Scholar.

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Study of chemical exposure, dementia risk funded by $11M grant

To better understand how day-to-day exposures to chemicals earlier in life can contribute to conditions like Alzheimer’s disease later on, researchers received an $11 million National Institutes of...

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Study links liver-brain communication to daily eating patterns

A Penn study showed disconnecting nerve connection corrects overeating and weight gain caused by a defective “liver clock".

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Penn Medicine, AHA Team Up to Take Down High Blood Pressure

Penn Medicine, the American Heart Association, and community organizations team up to take down high blood pressure in West and Southwest Philadelphia.

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Report comes as Washington considers ending the use of 14C jobs

Findings include policy considerations for lawmakers to consider as a new Congress takes shape.

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Inconsistencies of Genetic Markers for Predicting Heart Disease

Penn study suggests polygenic risk scores may provide conflicting results for detecting heart disease risk.

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UPHS releases sweeping Climate and Sustainability Action Plan

The plan outlines an ambitious roadmap to become the nation’s most eco-friendly health care organization.

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Health Care Reviews Tank Following COVID Pandemic

After the COVID-19 pandemic struck, online reviews of health care facilities dropped significantly, and they have not yet fully recovered, according to a new analysis led by researchers at the Perelman...

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Penn Medicine at the 2024 ASH Annual Meeting

Researchers from the Abramson Cancer Center and Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in blood cancer and benign hematology research at...

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Penn Medicine and IBX Announce New Long-Term Agreement

The University of Pennsylvania Health System and Independence Blue Cross have reached a long-term agreement on reimbursement rates for a new contract renewal, which would take effect on July 1, 2025.

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Penn Medicine partners with Mark Cuban’s Cost Plus Drugs

Penn Medicine has partnered with Mark Cuban's Cost Plus Drug Company through its innovative Cost Plus Marketplace in a strategic alliance that will allow Penn Medicine to secure the top 100 most...

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Keto diet metabolite may power up CAR T cells to kill cancer

A simple dietary supplement may provide a new, cost-effective approach to boost CAR T cell function, according to early findings shared at the ASH Annual Meeting.

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GBM organoids model patient response to CAR T cell therapy

For the first time, Penn Medicine researchers used lab-grown organoids created from tumors of individuals with glioblastoma to accurately model a patient’s response to CAR T cell therapy in real time.

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Researchers to advance imaging of Parkinson’s diseases

A Penn-led collaboration of radiology, computational chemistry, and neurology experts will identify and test new tracers for PET scans to help diagnose and monitor disease.

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Generic platinum chemo shortages did not increase deaths

An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin...

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Driving down postpartum high blood pressure

Perelman School of Medicine researchers are launching a $12.5 million study to improve postpartum blood pressure management and long-term cardiovascular health for patients with hypertensive disorders...

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Two health startups receive Penn Medicine-Wharton funds

The startups seek to address workplace burnout and racial inequity in maternal care.

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Cellular structures link to kidney cancer treatment outcomes

New research from the Berger Lab reveals that nuclear speckle patterns in kidney tumors may influence treatment outcomes for clear cell renal cell carcinoma, offering a path toward more personalized...

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New CAREs grants behind Penn Medicine volunteer projects

37 projects were awarded funds to support health system and medical school volunteer work.

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Genetic testing for risk of opioid misuse remains unproven

New research questions the usefulness of 15 genetic variants from an algorithm meant to predict opioid use disorder risk that was recently granted pre-marketing approval by the Food and Drug...

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Using AI to uncover hospital patients’ long COVID care needs

A new machine learning technique could help inform clinical decision- making across hospital systems to address the challenges of long COVID-19 care.

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Racism linked to higher postpartum blood pressure

Mothers of color who faced racism or microaggressions during obstetric care had higher blood pressure after delivering their babies compared to people of color who did not report racism during their care.

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AI analyzes 30k data points per pixel in cancer search

A new AI tool can search through data and images for much more precise information on cancer treatment effectiveness than what can be seen in CT or MRI scans.

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Penn Medicine scientists develop tiny anticancer weapon

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of...

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Researchers develop guidelines to diagnose common memory disorder

Limbic-predominant age-related TDP-43 encephalopathy can progress slower and cause less impairment of cognitive functions than other types of dementia.

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Penn Medicine names Pari V. Pandharipande Chair of Radiology

Pari V. Pandharipande, MD, MPH, FACR, a nationally renowned physician-scientist at The Ohio State University (OSU) College of Medicine and Wexner Medical Center, has been named Penn Medicine Chair of...

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Research sheds light on risks related to firearms and opioids

Research could shed more light on the risks related to firearms and opioids.

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Susan Domchek honored by ASCO for cancer prevention work

Susan M. Domchek, MD, FASCO, has been recognized by the American Society of Clinical Oncology with one of the society’s highest honors, as the 2025 recipient of the ASCO-American Cancer Society Cancer...

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No evidence that CAR T cell therapy causes secondary cancers

Researchers found no evidence that CAR T cell therapy caused any type of secondary cancer in the modified T cells, according to new analysis from the Perelman School of Medicine and the Abramson Cancer...

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7 Penn, CHOP faculty elected to ASCI

The members are among 99 physician-scientists from 46 institutions recognized for excellence across academic medicine.

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AI tool helps find life-saving medicine for rare disease

Set to enter hospice care, a patient with idiopathic multicentric Castleman’s disease is now in remission after treatment with a medication predicated as the top treatment by an AI-guided analysis.

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Higher cancer risk for kidney transplant recipients linked to EBV

Over 90% of U.S. adults have had Epstein-Barr virus (EBV), but EBV-negative kidney transplant patients face a serious risk. A Penn study finds they may develop PTLD, a life-threatening immune disorder,...

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Researchers create genetic map tied to kidney disease

Creation of the most complete map of more than 1000 genes that influence kidney function could help experts diagnose and design targeted treatments for kidney disease.

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Rate of suicide higher in individuals with headaches

Suicide attempt and completion was highest among individuals with headaches from head injuries, but also elevated in individuals with mild headaches, Penn research finds.

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Transformational gift to accelerate Penn Medicine care

The Pavilion will be renamed to recognize Catherine and Anthony Clifton’s historic philanthropic commitment that will usher in a new era of innovation.

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Text message tool addresses "time toxicity" for cancer patients

A pilot study shows it’s possible to use digital technology to safely reduce the amount of time some patients with cancer spend receiving care.

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AI ‘scribe’ increases face-to-face time with patients

Using an artificial intelligence-powered system to “listen” to patient visits and take notes increased clinician face time with patients and reduced after-hours work.

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New mRNA therapy could repair damaged lungs

Penn researchers designed an organ-specific mRNA and lipid nanoparticle therapy which could lead to new targeted treatments for damaged organs.

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3 Penn papers in Clinical Research Forum Top 10

Three studies led by Perelman School of Medicine faculty were chosen among the nation’s most impactful clinical research publications.

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Diabetic eye disease up, but most severe forms down

Data showed that while diabetes-related eye diseases doubled since 2014, the most severe forms of the disease have decreased.

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Patients with disabilities less likely to feel respect from docs

Analysis shows that patients with disabilities were both less likely to feel respect from their doctors and less likely to feel their doctors explained things well.

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Four Penn cancer researchers elected to the AACR Academy

Garrett M. Brodeur, MD, Susan Domchek, MD, Stephan Grupp, MD, PhD, and Robert Vonderheide, MD, DPhil, have been elected to the AACR Academy.

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Controlling cell acidity could be key to autoimmune disease

Genetic screening may have unlocked a path for treating the severe inflammation associated with many immune diseases by regulating one protein’s role in helping another protein control cell acidity.

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Older adults may be more resistant to bird flu

Older adults who were exposed to seasonal flu viruses that circulated prior to 1968 are more likely to have some protection against H5N1, and that children would benefit more from H5N1 vaccines.

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Immunotherapy boosts KRAS-targeted therapy in pancreatic cancer

Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.

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Small incentives drive lasting seatbelt habits

When drivers of connected cars were promised a share of reward money for weekly streaks of always wearing their seatbelts, they buckled up more, even after the program ended.

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Early anti-obesity medications boost weight loss

Struggling to lose weight with diet & exercise? New research shows adding anti-obesity meds after just 1 month of therapy doubles weight loss, offering hope for those who falter with lifestyle...

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DNA-LNPs: A Safer, Longer-Lasting Gene Therapy Breakthrough

The first safe & effective DNA-loaded lipid nanoparticles (DNA-LNPs) picks up where mRNA left off.

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Meniscus injuries may soon be treated by customizable hydrogel

A new 3D-printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears.

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